Eligible Applicants:
All types of applicants are eligible to apply, except nonprofit organizations described in section 501(c)(4) of the Internal Revenue Code of 1986 that engaged in lobbying activities after December 31, 1995
Notes for Applicants of All types:
(a) Individual applicants are unlikely to possess the skills, abilities, and resources to successfully accomplish the objectives of this NOFO. Individual applicants are encouraged to address this concern in their applications and to demonstrate how they will accomplish the objectives of this NOFO.
(b) Non-domestic applicants are advised that successful applications from non-domestic applicants include a detailed demonstration of how the applicant possesses skills, resources, and abilities that do not exist among potential domestic applicants.
Eligible Activities:
This is the Office of Science’s open application call for FY26 and may include a variety of eligible activities related to research and development. A non-exhaustive list of examples include:
(a) Advanced Scientific Computing Research (ASCR) such as applied mathematics, computer science, and computational partnerships
(b) Basic Energy Sciences such as biomolecular materials, gas phase chemical physics, synthesis and processing science, and geosciences
(c) Biological and Environmental Research (BER) such as microbiome research, atmospheric process research, environmental systems process research, and earth-energy systems modeling
(d) Fusion Energy Sciences (FES) such as Artificial Intelligence and machine learning for fusion and plasma science, high energy density physics, public-private partnerships
(e) High Energy Physics (HEP) such as experimental research at the energy frontier in high energy physics, accelerator science and technology R&D in high energy physics, and theoretical research in high energy physics
(f) Nuclear Physics (NP) such as medium energy nuclear physics, heavy ion nuclear physics, fundamental symmetries, and nuclear theory
(g) Isotope R&D and Production (IRP) such as targetry and isotope production research, biological tracers, imaging, and therapeutics
This funding does not support an applicant’s commercial activity. This NOFO seeks to support basic research to advance understanding rather than to address commercial opportunities. Applications that propose research related to current commercial activity or current customer needs may be declined without merit review. All for-profit applicants must include a description, not to exceed 200 words of how their proposed work will advance scientific understanding of a basic and fundamental nature as an appendix to the Project Narrative.